Yang Lei Selected Research

Glutaral (Glutaraldehyde)

1/2022	A PEGylation method of fabricating bioprosthetic heart valves based on glutaraldehyde and 2-amino-4-pentenoic acid co-crosslinking with improved antithrombogenicity and cytocompatibility.
1/2022	Arginine-grafted porcine pericardium by copolymerization to improve the cytocompatibility, hemocompatibility and anti-calcification properties of bioprosthetic heart valve materials.
1/2019	Hydrogel hybrid porcine pericardium for the fabrication of a pre-mounted TAVI valve with improved biocompatibility.

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Yang Lei Research Topics

Disease

21	Neoplasms (Cancer) 03/2022 - 01/2013
10	Infections 04/2020 - 01/2013
10	Aortic Valve Stenosis (Aortic Stenosis) 01/2016 - 11/2011
6	Prostatic Neoplasms (Prostate Cancer) 11/2021 - 07/2019
4	Major Depressive Disorder (Major Depressive Disorders) 01/2018 - 01/2013
3	Glioma (Gliomas) 11/2022 - 12/2013
3	Bacterial Infections (Bacterial Infection) 01/2022 - 03/2019
3	Thrombosis (Thrombus) 01/2022 - 01/2022
3	Alzheimer Disease (Alzheimer's Disease) 12/2021 - 12/2018
3	Inflammation (Inflammations) 01/2021 - 04/2013
3	Cerebral Hemorrhage 01/2019 - 01/2018
3	Brain Ischemia (Cerebral Ischemia) 07/2018 - 12/2008
3	Reperfusion Injury 07/2018 - 12/2008
3	Vascular Calcification 04/2015 - 11/2013
3	Glioblastoma (Glioblastoma Multiforme) 02/2014 - 08/2013
2	Carcinogenesis 03/2022 - 01/2020
2	Stroke (Strokes) 01/2022 - 07/2018
2	COVID-19 07/2021 - 12/2020
2	Disease Resistance 02/2021 - 02/2014
2	Liver Cirrhosis (Hepatic Cirrhosis) 02/2021 - 10/2019
2	Head and Neck Neoplasms (Head and Neck Cancer) 01/2021 - 01/2021
2	Wounds and Injuries (Trauma) 01/2019 - 11/2017
2	Lymphoma (Lymphomas) 01/2019 - 12/2013
2	Brain Injuries (Brain Injury) 01/2019 - 06/2015
2	Liver Diseases (Liver Disease) 10/2017 - 01/2016
2	Premature Birth (Birth, Premature) 03/2017 - 01/2017
2	Monckeberg Medial Calcific Sclerosis 12/2014 - 11/2013
2	Atherosclerosis 07/2014 - 04/2014
2	Acute Coronary Syndrome 07/2009 - 11/2008
2	Ischemia 12/2008 - 11/2008
2	Hypoxia (Hypoxemia) 04/2008 - 02/2008
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 03/2022
1	Chronic Kidney Failure (Chronic Renal Failure) 01/2022
1	Epilepsy (Aura) 01/2022
1	Abdominal Pain (Pain, Abdominal) 01/2022
1	Cognitive Dysfunction 01/2022
1	Colitis 01/2022
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022
1	Margins of Excision 01/2022
1	Myasthenia Gravis 10/2021
1	Brain Neoplasms (Brain Tumor) 08/2021

Drug/Important Bio-Agent (IBA)

8	Proteins (Proteins, Gene)FDA Link 03/2022 - 04/2008
6	Biomarkers (Surrogate Marker)IBA 03/2022 - 01/2013
4	Peptides (Polypeptides)IBA 07/2021 - 01/2013
4	Protons (Proton)IBA 01/2021 - 01/2019
4	LigandsIBA 01/2021 - 01/2013
3	RNA (Ribonucleic Acid)IBA 03/2022 - 08/2014
3	Glutaral (Glutaraldehyde)IBA 01/2022 - 01/2019
3	AluminumIBA 01/2022 - 12/2021
3	InterferonsIBA 01/2021 - 10/2017
3	Neuroprotective AgentsIBA 01/2019 - 11/2017
3	ElastinIBA 12/2014 - 11/2013
2	Biological ProductsIBA 01/2022 - 02/2014
2	tributyl phosphate (TBP)IBA 01/2022 - 01/2022
2	Nucleic AcidsIBA 07/2021 - 12/2020
2	MicroRNAs (MicroRNA)IBA 02/2021 - 06/2014
2	SolutionsIBA 12/2020 - 04/2013
2	Immunoglobulins (Immunoglobulin)IBA 06/2020 - 12/2013
2	Tyrosine (L-Tyrosine)FDA Link 04/2020 - 01/2019
2	Antiviral Agents (Antivirals)IBA 01/2019 - 01/2019
2	oxodiperoxo(pyridine- 2- carboxylate)vanadate(V)IBA 01/2019 - 07/2018
2	Ribavirin (Virazole)FDA LinkGeneric 01/2019 - 10/2017
2	glecaprevir and pibrentasvirIBA 01/2019 - 10/2017
2	Protease Inhibitors (Protease Inhibitor)IBA 01/2018 - 10/2017
2	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2018 - 01/2017
2	Docosahexaenoic AcidsIBA 03/2017 - 01/2017
2	Messenger RNA (mRNA)IBA 04/2015 - 12/2008
2	VaccinesIBA 01/2015 - 01/2015
2	Neuropilin-1IBA 02/2014 - 12/2013
2	PolyethyleneimineIBA 02/2014 - 12/2013
2	monomethoxypolyethylene glycol (MPEG)IBA 02/2014 - 08/2013
2	poly(ethylene glycol)-co-poly(ethyleneimine)IBA 02/2014 - 12/2013
2	Neurofibromin 2 (Merlin)IBA 07/2009 - 11/2008
1	Ephrin-A1 (Ephrin A1)IBA 03/2022
1	aumolertinibIBA 01/2022
1	Indicators and Reagents (Reagents)IBA 01/2022
1	ProdrugsIBA 01/2022
1	tebipenemIBA 01/2022
1	L 084IBA 01/2022
1	NMDA receptor A1IBA 01/2022
1	Carbapenems (Carbapenem Antibiotics)IBA 01/2022
1	osimertinibIBA 01/2022
1	tau Proteins (tau Protein)IBA 12/2021
1	NeurotoxinsIBA 12/2021
1	AntagomirsIBA 02/2021
1	AnnexinsIBA 02/2021
1	Dimethylnitrosamine (Nitrosodimethylamine)IBA 02/2021
1	Biocompatible Materials (Biomaterials)IBA 01/2021
1	CXC ChemokinesIBA 01/2021
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2021

Therapy/Procedure

15	Radiotherapy 11/2022 - 12/2019
14	Therapeutics 03/2022 - 03/2009
9	Transcatheter Aortic Valve Replacement 07/2015 - 11/2011
3	Stents 01/2022 - 01/2017
3	Brachytherapy 11/2021 - 07/2019
2	Catheters 11/2021 - 09/2020
1	Renal Dialysis (Hemodialysis) 01/2022
1	Operative Time 01/2022
1	Drug Tapering 01/2022
1	Thymectomy 10/2021